Anterior Non-Granulomatous Uveitis in COVID-19

Hamidreza Hasani1 *

  1. Alborz University of Medical Sciences

Abstract: Since prevalence of the Severe Acute Respiratory Syndrome 2 (SARS-CoV-2), millions of infected people presented with various manifestations. Some studies report ocular complications, such as conjunctivitis and sub-conjunctival haemorrhage, as an initial manifestation of Corona Virus Disease 2019 (COVID-19). This article aims to report unilateral acute anterior non-granulomatous uveitis manifested in COVID-19. Systemic work up and laboratory results, confirmed the diagnosis.

Methods: A 37-year-old female patient with a history of hypothyroidism, fever, weakness and lethargy, throbbing chest pain, non-productive cough and diffuse painful redness of the left eye with positive COVID-19 polymerase chain reaction (PCR) test from nasopharyngeal and oropharyngeal swabs and erythrocyte sedimentation rate of 43 mm/h is reported.

Results: Demographically, the patient was a 37-year-old female. On ophthalmologic examination, right and left eye vision were 10/10 and 5.10, respectively. The relative afferent pupillary defect was negative. External ocular motility was within normal limits. On slit lamp biomicroscopy, conjunctival peri-limbal injection, 2+ cells and 3+ flares in the anterior chamber of the left eye, posterior synechiae was seen and the vitreous cavity was clear. Right eye examination was completely normal.

Conclusion: Covid-19 can be associated with ocular involvement as acute non-granulomatous anterior uveitis, which can be prevented ocular complications and vision loss if diagnosed and treated early. Acute anterior non-granulomatous uveitis can also be an early sign of Covid-19 disease, which should raise clinical suspicion of the disease and therefore reduce the morbidity and mortality of Covid-19 disease by starting timely treatment.





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