Can the failure of trabeculectomy in one eye predict the outcomes of trabeculectomy in the fellow eye?
Maryam Yadgari1 , Amir Arabi2 *, Kiana Hassanpour2
- Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science,
Shahid Beheshti University of Medical Sciences, Tehran, Iran.
- Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract: To evaluate the predicting value of trabeculectomy (Trab) outcomes in the contralateral eye for the success of Trab.
Methods: It is a retrospective study on 76 eyes from 38 patients who had undergone bilateral Trab with various intervals between the surgeries. One eye from each patient was randomly selected to be included in the “study eye” group. Success of Trab in the case and control eyes was defined according to the criteria of World Glaucoma Association. As the main outcome of the study, success of Trab was compared between eyes with different surgical outcomes of Trab in the fellow eye.
Results: The mean age of the patients was 58.97 ± 12.74 years. The most common type of glaucoma was primary open angle glaucoma (46.1%). A follow-up period of 12 months was considered for the outcomes of Trab in the study and control eyes. In 47.3% of the surgeries in the “study eye” group, Trab was associated with complete success, while 13.1% experienced surgical failure. Failure of Trab in the fellow eye and IOP>15 mmHg at 1-year visit following surgery in the contralateral eye were correlated with a lower rate of complete or partial success of Trab in the study eyes (OR= 0.119 and 0.318 with P= 0.02 and 0.39, respectively). Also, in cases who required ≥ 2 anti-hypertensive eye drops at 1-year visit in the contralateral eye, the rate of partial or complete success was lower (OR=0.52 with P=0.04).
Conclusion: In our subset of patients, surgical outcomes of Trab in the fellow eye could predict the Trab success in the study eye. Further studies with appropriate sample size and prospective design are required to approve the correlation of Trab outcomes between two eyes in a glaucoma patient.
