Outcomes of deep sclerectomy in Primary Open Angle Glaucoma versus Pseudoexfoliation Glaucoma
Ebrahim Azaripour Masoule1 *
- Eye Research Center, Department of Ophthalmology, Amiralmomenin Hospital, School of Medicine, Guilan University of
Medical Sciences, Rasht, Iran
Abstract: Deep sclerectomy represents an alternative to standard penetrating glaucoma surgery. The aim of this study is to compare the outcomes of and viscocanalostomy in eyes with primary open-angle glaucoma (POAG) versus eyes with pseudoexfoliation glaucoma (PEXG).
Methods: In this prospective non-randomized comparative study, eyes with POAG or PEXG were enrolled. Pre- and postoperative data including best corrected visual acuity (BCVA), intraocular pressure (IOP), and the number of antiglaucoma medications administered were recorded at each visit. All patients underwent deep sclerectomy. Complete success was defined as the IOP of 21 mmHg or less without the administration of medication while a qualified success reported the same IOP parameters either with or without the administration of medication.
Results: Thirty-four eyes with POAG and thirty-four with PEXG underwent deep sclerectomy. The mean follow-up time was 23.36 ± 8.8 months (range, 6–40 months). The mean postoperative IOP reduced significantly in both groups, although the mean IOP reduction was significantly greater in PEXG eyes (14.7 ± 8.9 vs 10.1 ± 7.7 mmHg) (P = 0.05). At the final follow-up visit, the mean postoperative IOP was 16.1 ± 3.1 and 18.6 ± 4.5 mmHg in the PEXG and POAG eyes, respectively (P = 0.001). A complete success rate of 88.9% and 75.9% was achieved in PEXG and POAG eyes, respectively (P = 0.07). The qualified success rate was 89% in the PEXG and 80.2% in POAG groups (P = 0.03).
Conclusion: Deep sclerectomy achieved significant IOP reduction and visual improvement in both POAG and PEXG patients. Our results indicated that in terms of IOP reduction, this procedure was more effective in treating PEXG.
