Evaluation of the effect of refractive errors on the vascular density analysis of optic nerve head by OCTA
Arezoo Miraftabi1 *, Navid Abolfathzadeh10 , Atousa Moghadam Fard10
- Eye Research Center, The Five Senses Health Institute, Rassoul Akram Hospital , Iran University, of Medical Sciences, Tehran, Iran
Abstract: The aim of the study was the determination of any difference between the vascular density of optic nerve heads between healthy low myopic, hyperopic, and emmetropic individuals.
Methods: Seventy-five eyes from 75 healthy subjects including 25 hyperopes,25 myopes, and 25 emmetropes entered in this prospective comparative study. The range of myopia was between was -1.00 to -6.00 and the range of hyperopia was +1.00-+4.00. The emmetropic patients had refraction between +1.00 to -1.00. Optical Coherence Tomography (OCT) and OCT-Angiography (OCT-A) were done for all participants.
Results: There was no difference between average peripapillary retinal nerve fiber layers between groups. The myopic eyes had a significantly larger axial length (P<0.001)
There was no significant correlation between axial length and vascular density of optic nerve head in our study.
The whole image RPC vascular density was 56.49±3.38 in emmetropic and 48.99±3.28 in myopic and 50.74±3.23 in hyperopic eye.(P =0.07)
We found no difference between whole image Radial Capillary Plexus (RCP) density in the superior and inferior parts between groups. The nasal RCP vascular density was significantly lower in myopic patients. (P<0.001)
Conclusion: Our study showed no difference between the whole density of the RCP in healthy myopic, hyperopic, and emmetropic eyes. We observed only a significant decrease in nasal sector density of RCP in myopic eyes.
